DIAL - De novo Identification of Alleles | Tool name | DIAL - De novo Identification of Alleles |
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| URL |
http://www.bx.psu.edu/miller_lab/ |
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| Important features | 1. DIAL (De novo Identification of Alleles), for identifying single-base substitutions between two closely related genomes without the help of a reference genome.
2. The method works even when the depth of coverage is insufficient for de novo assembly, and it can be extended to determine small insertions/deletions.
3. The use of DIAL to identify nucleotide differences among transcriptome sequences. |
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| Citations | Ratan A, Zhang Y, Hayes VM, Schuster SC, Miller W.
Calling SNPs without a reference sequence.
BMC Bioinformatics. 2010 Mar 15;11:130.
PMID: 20230626 |
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| Year of publication | 2010 |
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| Rank by usage frequency | 100 |
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| Comments | Requires installation of LASTZ in the path. |
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| Function | SNP discovery |
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| Category | Free, Downloadable |
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| License | MIT |
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| Status | |
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| Input file format | SFF files for Roche 454, FASTQ for Illumina/Solexa |
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| Output file format | |
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| Operating system | Linux 64 bit |
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| Operating language | C, Python |
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| Platform | Illumina/Solexa, Roche 454 |
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| Maintained by | Heracle BioSoft |
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| Downloadable file format | |
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| Submission file format | |
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